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There is a worldwide interest in studying SLC26A4 mutations that are responsible for enlarged vestibular aqueduct (EVA) in different ethnic background and populations. The spectrum of SLC26A4 mutations in Chinese population is yet to be fully characterized. In this study, all the 21 exons of SLC26A4 were screened in 107 Chinese patients with hearing loss(More)
Pancreatic cancer (PCa), which is now the fourth most frequent cause of cancer-related death, has a median survival of less than 6 months and a 5-year survival rate of <6%. The hallmarks of this cancer include poor outcome, short survival duration, and resistance to therapy. The poor prognosis of PCa is related to its local recurrence, lymph node and liver(More)
PURPOSES Robotic gastrectomy (RG), as an innovation of minimally invasive surgical method, is developing rapidly for gastric cancer. But there is still no consensus on its comparative merit in either subtotal or total gastrectomy compared with laparoscopic and open resections. METHODS Literature searches of PubMed, Embase and Cochrane Library were(More)
MicroRNAs are involved in the initiation and progression of pancreatic cancer. In this study, we showed that miR-221/222 is overexpressed in pancreatic cancer. MiR-221/222 overexpression significantly promoted pancreatic cancer cell proliferation and invasion while inhibiting apoptosis. The expression of the matrix metalloproteinases (MMPs) MMP-2 and MMP-9(More)
BACKGROUND/AIMS After a distal resection of the stomach, the continuity of the gastrointestinal tract can be restored by either a gastroduodenal anastomosis (Billroth I), a gastrojejunal anastomosis (Billroth II) or a Roux-en-Y gastrojejunostomy. There is still no consensus on the reconstruction technique of choice. The aim of this report was to assess the(More)
This paper describes our experiments on the cross-domain Chinese word segmentation task at the first CIPS-SIGHAN Joint Conference on Chinese Language Processing. Our system is based on the Conditional Random Fields (CRFs) model. Considering the particular properties of the out-of-domain data, we propose some novel steps to get some improvements for the(More)
BACKGROUND/AIMS Published data on the dose of imatinib to treat gastrointestinal stromal tumors seemed inconclusive. To derive a more precise estimation of dose of imatinib to treat gastrointestinal stromal tumors, a meta-analysis was performed. MATERIAL AND METHODS Studies have been identified by searching PubMed and Embase. Inclusion criteria were(More)
News comment is a new text genre which people use to express their opinions on recent news events. Different from normal text corpus, news comments have some particular properties. The named entities in the news comments usually use some wrongly written words, informal abbreviations or aliases, which bring great difficulties for machine detection and(More)
Intercellular genetic communication is an essential requirement for coordination of cell proliferation and differentiation and has an important role in many cellular processes. Gap junction channels possess large pore allowing passage of ions and small molecules between cells. MicroRNAs (miRNAs) are small regulatory RNAs that can regulate gene expression(More)
BACKGROUND The controversy of CpG island methylator phenotype (CIMP) in gastric cancer persists, despite the fact that many studies have been conducted on its relation with helicobacter pylori (H. pylori), Epstein-Barr virus (EBV), and microsatellite instability (MSI) and prognosis. To drive a more precise estimate of this postulated relationship, a(More)