Liang Zhao

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Promotion of colorectal cancer growth and metastasis by the LIM and SH3 domain protein 1.

Liang Zhao, Hui Wang, +8 authors Yanqing Ding
Gut
2010

BACKGROUND LIM and SH3 protein 1 (LASP-1), initially identified from a cDNA library of metastatic axillary lymph nodes of breast cancer patients, is a specific focal adhesion protein involved in… (More)

Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease

Melissa Kristine Middleton, Alicia Marie Zukas, +5 authors Ellen Pure
The Journal of experimental medicine
2006

Though Abl inhibitors are often successful therapies for the initial stages of chronic myelogenous leukemia (CML), refractory cases highlight the need for novel molecular insights. We demonstrate… (More)

Stathmin, a new target of PRL-3 identified by proteomic methods, plays a key role in progression and metastasis of colorectal cancer.

Ping Zheng, Yong-xia Liu, +7 authors Jianming Li
Journal of proteome research
2010

To better understand the role of PRL-3 in progression and metastasis of colorectal cancer (CRC), we searched for PRL-3 associated proteins using proteomic methods. We identified 39 PRL-3 associated… (More)

Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb

Liang Zhao, Evgeny A. Glazov, +5 authors Thomas J Gonda
Nucleic acids research
2011

To gain insight into the mechanisms by which the Myb transcription factor controls normal hematopoiesis and particularly, how it contributes to leukemogenesis, we mapped the genome-wide occupancy of… (More)

Occlusion Aware Unsupervised Learning of Optical Flow

Yang Wang, Yi Yang, Zhenheng Yang, Liang Zhao, Wei Xu
2018 IEEE/CVF Conference on Computer Vision and…
2018

It has been recently shown that a convolutional neural network can learn optical flow estimation with unsupervised learning. However, the performance of the unsupervised methods still has a… (More)

Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions

Hufeng Zhou, Shangzhi Gao, +8 authors Limsoon Wong
Biology Direct
2013

H. sapiens-M. tuberculosis H37Rv protein-protein interaction (PPI) data are essential for understanding the infection mechanism of the formidable pathogen M. tuberculosis H37Rv. Computational… (More)

Nanoparticles inhibit cancer cell invasion and enhance antitumor efficiency by targeted drug delivery via cell surface-related GRP78

Liang Zhao, Hongdan Li, +4 authors Rong-jian Su
International journal of nanomedicine
2015

Nanoparticles (NPs) which target specific agents could effectively recognize the target cells and increase the stability of chemical agents by encapsulation. As such, NPs have been widely used in… (More)

Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression.

Beth M. Tyler, Karen R Jansen, +8 authors Elliott Richelson
Proceedings of the National Academy of Sciences…
1999

Intraperitoneal injection of an unmodified antisense peptide nucleic acid (PNA) complementary to mRNA of the rat neurotensin (NT) receptor (NTR1) was demonstrated by a gel shift assay to be present… (More)

Derepression of c-Fos caused by microRNA-139 down-regulation contributes to the metastasis of human hepatocellular carcinoma.

Qin Fan, Minyi He, +6 authors Yawei Liu
Cell biochemistry and function
2013

This study investigates whether the anti-metastasis effect of microRNA-139 (miR-139) on hepatocellular carcinoma (HCC) is mediated through regulating c-fos expression. The expression levels of… (More)

MicroRNA-195 chemosensitizes colon cancer cells to the chemotherapeutic drug doxorubicin by targeting the first binding site of BCL2L2 mRNA.

Liang Zhao, Pengzhi Zhang, +5 authors Juan Qu
Journal of cellular physiology
2015

The mechanisms underlying doxorubicin (Dox) resistance in colon cancer cells are not fully understood. MicroRNA (miRNA) play important roles in tumorigenesis and drug resistance. However, the… (More)

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