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Fragile X syndrome is the most common inherited form of mental retardation. It is caused by loss of FMR1 gene activity due to either lack of expression or expression of a mutant form of the protein. In mammals, FMR1 is a member of a small protein family that consists of FMR1, FXR1, and FXR2. All three members bind RNA and contain sequence motifs that are(More)
In this paper, we present an example-based colorization technique robust to illumination differences between grayscale target and color reference images. To achieve this goal, our method performs color transfer in an illumination-independent domain that is relatively free of shadows and highlights. It first recovers an illumination-independent <i>intrinsic(More)
This paper presents a novel and effective approach to synthesize English handwriting in the user’s writing style. We select the most important features that depict the handwriting style, including character glyph, size, slant, and pressure, special connection style, letter spacing, and cursiveness. The features can be efficiently computed with the aid of(More)
In eukaryotic cells, the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and likely other RNPs is mediated by an assemblyosome, the survival of motor neurons (SMN) complex. The SMN complex, composed of SMN and the Gemins (2-7), binds to the Sm proteins and to snRNAs and constructs the heptameric rings, the common cores of Sm proteins,(More)
Human transportin1 (hTRN1) is the nuclear import receptor for a group of pre-mRNA/mRNA-binding proteins (heterogeneous nuclear ribonucleoproteins [hnRNP]) represented by hnRNP A1, which shuttle continuously between the nucleus and the cytoplasm. hTRN1 interacts with the M9 region of hnRNP A1, a 38-amino-acid domain rich in Gly, Ser, and Asn, and mediates(More)
Omnidirectional videos are usually mapped to planar domain for encoding with off-the-shelf video compression standards. However, existing work typically neglects the effect of the sphere-to-plane mapping. In this paper, we show that by carefully designing the mapping, we can improve the visual quality, stability and compression efficiency of encoding(More)
Even though the temporal information is lost, a still picture of moving animals hints at their motion. In this paper, we infer motion cycle of animals from the "motion snapshots" (snapshots of different individuals) captured in a still picture. By finding the motion path in the graph connecting motion snapshots, we can infer the order of motion snapshots(More)
Abnormal uterine bleeding after Norplant administration is primarily responsible for the high discontinuation rate of this safe and effective long-acting implantable progestin-only contraceptive agent. Although tissue factor (TF) is the primary initiator of hemostasis, previous studies indicated that Norplant-associated bleeding persists despite relatively(More)
XRCC1 plays a central role in mammalian DNA repair processes. Two polymorphisms of XRCC1, rs1799782 (Arg > Trp at codon 194) and rs25487 (Arg > Gln at codon 399), are common in the Han Chinese population. Our objective was to analyze the relationship between these two functional single-nucleotide polymorphisms (SNPs) and systemic lupus erythematosus (SLE)(More)
Interleukin (IL)-18, an important mediator of innate and adaptive immunity, plays multiple roles in chronic inflammation, in autoimmune diseases, in a variety of cancers and in number of infectious diseases. IL-18 promoter polymorphisms have been also noted associated with various inflammatory diseases. We investigated the association of IL-18 promoter(More)