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We describe a new repressible binary expression system based on the regulatory genes from the Neurospora qa gene cluster. This "Q system" offers attractive features for transgene expression in Drosophila and mammalian cells: low basal expression in the absence of the transcriptional activator QF, high QF-induced expression, and QF repression by its(More)
The increasing use of information technology (IT) has resulted in a need for evaluating the productivity impacts of IT. The contemporary IT evaluation approach has focused on return on investment and return on management. IT investment has impacts on different stages of business operations. For example, in the banking industry, IT plays a key role in(More)
An appropriate performance measurement system is an important requirement for the effective management of a supply chain. Two hurdles are present in measuring the performance of a supply chain and its members. One is the existence of multiple measures that characterize the performance of chain members, and for which data must be acquired; the other is the(More)
We characterize an inhibitory circuit motif in the Drosophila olfactory system, parallel inhibition, which differs from feedforward or feedback inhibition. Excitatory and GABAergic inhibitory projection neurons (ePNs and iPNs) each receive input from antennal lobe glomeruli and send parallel output to the lateral horn, a higher center implicated in(More)
Particle tracking is of key importance for quantitative analysis of intracellular dynamic processes from time-lapse microscopy image data. Because manually detecting and following large numbers of individual particles is not feasible, automated computational methods have been developed for these tasks by many groups. Aiming to perform an objective(More)
Data envelopment analysis (DEA) is a method for measuring the efficiency of peer decision making units (DMUs). This tool has been utilized by a number of authors to examine two-stage processes, where all the outputs from the first stage are the only inputs to the second stage. The current article examines and extends these models using game theory concepts.(More)