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BACKGROUND AND PURPOSE Hemodynamics is often recognized as one of the major factors in aneurysm rupture. Flow impingement, greater pressure, and abnormal wall shear stress are all indications for aneurysm rupture. Characterizing wall shear stress for intracranial aneurysms at similar anatomic locations may help in understanding its role. MATERIALS AND(More)
Magnetic Resonance Angiography (MRA) has become a routine imaging modality for the clinical evaluation of obstructive vascular disease. However, complex circulatory flow patterns, which redistribute the Magnetic Resonance (MR) signal in a complicated way, may generate flow artifacts and impair image quality. Numerical simulation of MRAs is a useful tool to(More)
BACKGROUND AND PURPOSE Hemodynamics is an important factor in the development and rupture of cerebral aneurysms. Current techniques for measuring blood flow in cerebral aneurysms suffer from various limitations and have not been able to address our clinical needs. A new technique has been developed for effective evaluation of intra-aneurysmal flow based on(More)
BACKGROUND AND PURPOSE The options for treating giant fusiform basilar aneurysms are limited, and the potential impact of planned interventions is difficult to assess. We developed a computational framework to evaluate the impact that interventions might have on hemodynamic conditions. METHODS A computational fluid dynamics approach was used to determine(More)
BACKGROUND AND PURPOSE Hemodynamics may predispose aneurysms to rupture; however, hemodynamic descriptors that can describe aneurysm growth are not well understood. We examined the relationship between hemodynamics and growth of 2 fusiform basilar artery aneurysms in an effort to define hemodynamic variables that may be helpful in predicting aneurysmal(More)
OBJECTIVE The goal of this study was to use phase-contrast magnetic resonance imaging and computational fluid dynamics to estimate the hemodynamic outcome that might result from different interventional options for treating a patient with a giant fusiform aneurysm. METHODS We followed a group of patients with giant intracranial aneurysms who have no clear(More)
Flow impingement is regarded as a key factor for aneurysm formation and rupture. Wall shear stress (WSS) is often used to evaluate flow impingement even though WSS and impinging force are in two different directions; therefore, this raises an important question of whether using WSS for evaluation of flow impingement size is appropriate. Flow impinging(More)
SUMMARY We present our initial experience of concentric-filling technique using MicruSphere 3D coils (Micrus Endovascular, San Jose, CA) in the treatment of intracranial aneurysms. 149 intracranial saccular aneurysms in 142 consecutive patients (mean age 56.6-/+12.7, ruptured in 54 (36.2%)) were treated with the concentric-filling technique. The mean(More)
BACKGROUND Cerebral artery dissection remains a significant cause of stroke, and the mainstay of treatment has been medical management with anticoagulation, although flow-diverting stents have been used in some cases of arterial dissection resistant to medical management. METHODS We present a case report of bilateral vertebral artery stenting using(More)
Stents play an important role in management of cerebral aneurysms. A stent reconstructs the parent artery, assists coil embolization, and decreases flow activity within an aneurysm. However, an in-stent stenosis often occurs within the stented artery and compromises the circulation at the parent artery. Hemodynamic basis of re-stenoses from aneurysm(More)