• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
  • Alison C. Pridmore, David H. Wyllie, +4 authors Robert Charles Read
  • Biology, Medicine
  • The Journal of infectious diseases
  • 2001
  • Meningococcal disease severity correlates with circulating concentrations of lipopolysaccharide (LPS) and proinflammatory cytokines. Disruption of the lpxA gene of Neisseria meningitidis generated aContinue Reading
  • Peter van der Ley, Liana Steeghs, Hendrik Jan Hamstra, Jan Bart Ten Hove, B Zomer, Loek van Alphen
  • Biology, Medicine
  • Infection and immunity
  • 2001 (First Publication: 1 October 2001)
  • Two genes homologous to lpxL and lpxM from Escherichia coli and other gram-negative bacteria, which are involved in lipid A acyloxyacylation, were identified in Neisseria meningitidis strain H44/76Continue Reading
  • Stéphanie Genevrois, Liana Steeghs, Paul J M Roholl, Jean-Jacques Letesson, Peter van der Ley
  • Biology, Medicine
  • The EMBO journal
  • 2003 (First Publication: 15 April 2003)
  • In Gram-negative bacteria, lipopolysaccharide and phospholipid biosynthesis takes place at the inner membrane. How the completed lipid molecules are subsequently transported to the outer membraneContinue Reading
  • Liana Steeghs, Sandra J van Vliet, +9 authors Jan G. J. van de Winkel
  • Medicine, Biology
  • Cellular microbiology
  • 2006 (First Publication: 1 February 2006)
  • Neisseria meningitidis lipopolysaccharide (LPS) has been identified as a major determinant of dendritic cell (DC) function. Here we report that one of a series of meningococcal mutants with definedContinue Reading
  • Andries van Mourik, Liana Steeghs, +4 authors M M Wösten
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2010 (First Publication: 21 May 2010)
  • Modification of the lipid A moiety of bacterial lipopolysaccharide influences cell wall properties, endotoxic activity, and bacterial resistance to antimicrobial peptides. Known modifications areContinue Reading
  • Jeroen Geurtsen, Liana Steeghs, +5 authors Peter van der Ley
  • Biology, Medicine
  • Infection and immunity
  • 2006 (First Publication: 1 October 2006)
  • Lipopolysaccharide (LPS) is one of the major constituents of the gram-negative bacterial cell envelope. Its endotoxic activity causes the relatively high reactogenicity of whole-cell vaccines.Continue Reading