AIM To conduct a placebo-controlled functional brain imaging study to assess the effect of the 5-hydroxytryptamine-3 receptor antagonist, alosetron, on irritable bowel syndrome symptoms, regional brain activation by rectosigmoid distension and associated perceptual and emotional responses. METHODS Fifty-two non-constipated irritable bowel syndrome… (More)
Paraganglioma arising in the thoracic extradural space is an uncommon tumor, with only four cases previously reported. The authors review the clinical and pathological features of thoracic paraganglioma and compare them to the more common paraganglioma of the cauda equina.
BACKGROUND Currently, no studies have investigated interinstrument reliability of the ActiGraph (AG) GT3X+ in free-living conditions. METHODS Nineteen adults (11 males, 8 females; aged 36.8 ± 11.9 years) wore a pair of AG's (one on each hip), during all waking hours for 1 day. Raw outputs were generated for total counts, steps, wear time and mean counts… (More)
An aggressive surgical strategy was applied to cranial gunshot wound victims at Cook County Hospital in Chicago from 1983 to 1992. A series of 480 patients with an overall mortality rate of 34% is presented. A total of 150 patients underwent craniotomy with an operative mortality rate of 21%. Criteria for operation were Glasgow Coma Scale scores of 3… (More)
Two young males with a high degree of consanguinity presented with similar brainstem gliomas. As the patients were raised separately, their presentation with similar tumors suggests a genetic basis for the occurrence of these gliomas.
Increased frequency of reoperation in neurosurgery has made the microscopic examination of tissue from previously operated sites more common. Various synthetic materials are in common use in neurosurgery, and these can cause clinical complications as well as presenting a diagnostic dilemma for the pathologist. The microscopic appearance of synthetic… (More)
Even this information is only partial. To study fully the effects of treatment would require optimal care at all points from time of injury, including rapid prehospital resuscitation, rapid transport to an optimally equipped and staffed hospital, immediate evaluation and treatment of the initial injury and all complications, rapid and comprehensive… (More)