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  • Lia Tescione, James Lambropoulos, Madhava Ram Paranandi, Helena Yusuf Makagiansar, Thomas Ryll
  • Chemistry, Medicine
  • Biotechnology and bioengineering
  • 2015
  • A bench scale cell culture model representative of manufacturing scale (2,000 L) was developed based on oxygen mass transfer principles, for a CHO-based process producing a recombinant human protein.Expand
  • Garima Chaudhary, Robin Hang Luo, Meena S. George, Lia Tescione, Anurag Khetan, Henry Lin
  • Chemistry, Medicine
  • Biotechnology and bioengineering
  • 2020 (First Publication: 22 February 2020)
  • There are three main potential sources for cell shear damage existing in stirred tank bioreactors. One is the potential high energy dissipation in the immediate impeller zones; another from small gasExpand