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[Effects of fluoride on osteoclastic activity of rats in vitro].
F fluoride can enhance the MMP-9 mRNA expression in cultured osteoclasts of rats with varied doses of fluoride, in a dose-response pattern but without statistical significance.
Reversal of MDR1 gene-dependent multidrug resistance using short hairpin RNA expression vectors.
BACKGROUND RNA interference using short hairpin RNA (shRNA) can mediate sequence-specific inhibition of gene expression in mammalian cells. A vector-based approach for synthesizing shRNA has been…
Study on the bone marrow mesenchymal stem cells induced drug resistance in the U937 cells and its mechanism.
MSCs play a role in modulating the proliferation of U 937 cells and response of U937 cells to DNR, and Bcl-XL apoptosis-inhibiting gene may be most important in determining the sensitivity of leukemic cells to treatment.
[Study of apoptosis gene expression in U937 cells induced by adhesion culture with mesenchymal stem cell].
- Yu-mei Lin, Gui-zhen Zhang, Zhen-xia Lu, Zong-xiang Leng, Li-sha Bu, Shen Gao
- Biology, MedicineZhonghua xue ye xue za zhi = Zhonghua xueyexue…
- 1 April 2006
Adhesion culture with MSCs can lead to growth suppression and decrease natural apoptosis of U937 cells, but Bcl-XL may be of the most importance.
[Study on multipotential differentiation of human bone marrow mesenchymal stem cells in vitro].
- Ying Chang, Xin Qi, Li-sha Bu, Zhongxin Xu
- Biology, MedicineZhongguo wei zhong bing ji jiu yi xue = Chinese…
- 1 February 2005
Human bone marrow MSCs have the capability of multipotential differentiation in vitro and expressed neuron-specific enolase and neurofilament in vitro.
Biological features of hMSC and effects of bFGF on its proliferation
HMSC can be expanded in vitro rapidly and the effect of bFGF on hMSC proliferation is in positive dose-effect manner.
Impact of human resistin on glucose uptake in adipocytes and its mechanism
The results suggested that human resistin impaired glucose uptake in adipoeytes via stimulating proliferation of preadipocytes and suppressing adipocyte differentiation, and metformin reversed the inhibition imposed by resistin on adipogenesis.