Li-jun Sun

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AIM Gene therapy represents a promising therapeutic strategy for hepatocellular carcinoma (HCC). To improve the ratio of killing efficacy on tumor cells to side-effect on normal cells, we constructed an oncolytic adenovirus vector, AdSu-hE, expressing the human endostatin (hE) gene, in which the chimeric promoter of human epidermal growth factor receptor 2(More)
BACKGROUND & OBJECTIVE Glioma cells can be induced in vitro from low differentiation state to high differentiation state with differentiation-inducing agents, as our previous studies have showed. However, the relevant molecular mechanisms remained unclear. This paper was to establish differentiation-inducing gene expression pedigree of glioma cells and(More)
NAC transcription factors belong to a unique class of transcription factors in plants. The common characteristics of the NAC proteins are the presence of a conserved NAC domain, comprising of about 150 amino acids in N-terminals and a highly variable transcriptional regulation region in C-terminals. Extensive studies have revealed that NAC transcription(More)
Forkhead-box (FOX) transcription factors comprise a large gene family that contains more than 50 members in man. Extensive studies have revealed that they not only have functions in control of growth and development, but also play important roles in different diseases, especially in cancer. However, biological functions for most of the members in the FOX(More)
The objective of this work was to determine the bacterial strains and factors that most efficiently degrade T-2 toxin in foods or animal feed. To determine the most efficient strain and optimal incubation times for degradation of T-2, the rate of T-2 removal by three lactic acid bacteria strains was quantified by liquid chromatography plus tandem mass(More)
The force due to electromagnetic pick-up can affect the performance of small pipeline turbine flow sensor. Based on electric eddy current, a new pick-up was designed for eliminating the effect of reluctance torque in traditional pick-up. The range ability of DN4mm, DN6mm and DN10mm turbine flow sensor were expanded to 10∶1. The reliability of(More)
Detection of phytohormones in situ has gained significant attention due to their critical roles in regulating developmental processes and signaling for defenses in plants at low concentration. As one type of plant hormones, salicylic acid has recently been found to be one of pivotal signal molecules for physiological behaviors of plants. Here we report the(More)
OBJECTIVE To evaluate the effects of intratympanic methylprednisolone injection by microcatheter in diabetics with a sudden hearing loss. METHODS From July 2005 to November 2009, 113 diabetics with a sudden hearing loss within an onset of 10 days at our department were recruited. But they received no previous intervention and were assigned to treatment(More)
OBJECTIVE To evaluate the effect of intramyocardial administration of basic fibroblast growth factor (bFGF) on the angiogenesis and on the expression of bFGF and vascular endothelial growth factor (VEGF) in infarcted myocardium. METHODS Twenty-four mongrel dogs were randomized into control group and therapeutic group. Acute myocardial infarction was made(More)