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Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human.
The ratio of nonsynonymous/synonymous nucleotide substitution in palm civets collected 1 yr apart from different geographic locations is very high, suggesting a rapid evolving process of viral proteins in civet as well, much like their adaptation in the human host in the early 2002-2003 epidemic.
Serotype 1-Specific Monoclonal Antibody-Based Antigen Capture Immunoassay for Detection of Circulating Nonstructural Protein NS1: Implications for Early Diagnosis and Serotyping of Dengue Virus
  • Hua Xu, B. Di, X. Che
  • Biology, Medicine
    Journal of Clinical Microbiology
  • 1 August 2006
The findings suggest that the serotype-specific MAb-based NS1 antigen capture ELISA may be a valuable tool for early diagnosis and serotyping of DV infections, while also providing a standardized assay for the analysis of a great number of clinical samples with convenience and cost-effectiveness.
[Analysis on the characteristics of blood serum Ab-IgG detective result of severe acute respiratory syndrome patients in Guangzhou, China].
Blood serum Ab-IgG characteristics of severe acute respiratory syndrome (SARS) patients in Guangzhou are probed to investigate the related factors and it was impossible for the sub-clinic infection of SARS-CoV virus.
Establishment of a fluorescent polymerase chain reaction method for the detection of the SARS-associated coronavirus and its clinical application.
The F-PCR method established may be a rapid, accurate and efficient way for screening and for the early diagnosis of SARS patients.
Characteristics of the pathogenic isolates from the SARS patients in Guangzhou
The lung tissues from the SARS bodies were examined by the electronic microscope and the isolated pathogen were identified through RT-PCR and Immunofluorenscent stain was performed to test the antibody of the patient's convalescent phase serum.