Jiao Lou16
Wei Chen15
16Jiao Lou
15Wei Chen
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BACKGROUND Excess body weight measured as body mass index (BMI) has a positive association with risk of common cancers. However, previous meta-analyses related to BMI and liver cancer had inconsistent results. The purpose of the current study is to establish a nonlinear dose-response relationship between BMI and incidence risk of liver cancer. METHODS A(More)
In a distributed multiuser game, entities need to communicate their state information to other entities. Usually only a subset of the game's entities are interested in information being disseminated by a n y particular entity. In a large scale distributed game with many machines interconnected by a wide-area network, broadcasting messages containing each(More)
Peer-to-peer systems contain a collection of equivalent entities that form an application-layer overlay network. Each entity acts as client, server, and overlay network router. Peer-to-peer systems enable the rapid development of distributed applications; in short order, peer-to-peer file sharing has become one of the most popular Internet applications.(More)
BACKGROUND Neural Tube Defects (NTDs) are among the most prevalent and most severe congenital malformations worldwide. Polymorphisms in key genes involving the folate pathway have been reported to be associated with the risk of NTDs. However, the results from these published studies are conflicting. We surveyed the literature (1996-2011) and performed a(More)
The dopaminergic system plays a pivotal role in the central nervous system via its five diverse receptors (D1–D5). Dysfunction of dopaminergic system is implicated in many neuropsychological diseases, including attention deficit hyperactivity disorder (ADHD), a common mental disorder that prevalent in childhood. Understanding the relationship of five(More)
BACKGROUND Metabolic syndrome traits play an important role in the development of colorectal cancer. Adipokines, key metabolic syndrome cellular mediators, when abnormal, may induce carcinogenesis. METHODOLOGY/PRINCIPAL FINDINGS To investigate whether polymorphisms of important adipokines, adiponectin (ADIPOQ) and its receptors, either alone or in(More)
BACKGROUND A common genetic variant, rs4939827, located in SMAD7, was identified by two recent genome-wide association (GWA) studies to be strongly associated with the risk of colorectal cancer (CRC). However, the following replication studies yielded conflicting results. METHOD AND FINDINGS We conducted a case-control study of 641 cases and 1037 controls(More)