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PURPOSE Obstructive sleep apnea hypopnea syndrome (OSAHS) is an independent risk factor for development of hypertension. Epidemiological surveys have found that risk of cardiovascular diseases increased in postmenopausal women. However, it is not well known about the profiles of hypertension of women with OSAHS in their different reproductive stages. This(More)
Little is known about combined effect of obstructive sleep apnea (OSA) and chronic smoking on cognitive impairment. We aimed to determine whether smoking synergizes with OSA in deteriorating cognitive function and whether smoking cessation contributes to cognitive benefits. One hundred and eighteen male patients were enrolled in the study and asked to(More)
OBJECTIVE To evaluate the long-term efficacy and safety of bronchial thermoplasty (BT) in the treatment of patients with moderate-to-severe persistent asthma. METHODS We therefore performed a systematic literature review of peer-reviewed studies focusing on BT intervention in asthma control published between January 2000 and June 2014. Three randomized(More)
BACKGROUND Abdominal aortic aneurysms (AAA) are rare in children and are associated with significant morbidity and mortality as in adults. We summarize our experience in the diagnosis and management of AAAs in 6 children at a single institution. METHODS The clinical data of 6 pediatric patients with AAAs treated at our hospital from November 2005 to(More)
UNLABELLED Acetylcholine (ACh) signaling is involved in a wide range of processes, including arousal, attention, and learning. An increasing number of studies indicate that cholinergic control of these functions is highly deterministic, mediated by synaptic afferents that generate reliable and precise responses in postsynaptic neurons. However, mechanisms(More)
BACKGROUND Obesity is linked to variation of lung volume; however, it is still unclear whether a sex difference exists. The study aimed to find out the effect of obesity on lung volume and sex difference among the Chinese population. METHOD Pulmonary function test results were collected from 300 patients (aged 18 to ~80 years) with normal airway function(More)
Open Access prospective study showed that smokers were younger and were more likely to experience severe snoring with increased nasal obstruction, lower nasal volumes after decongestion and a longer soft palatal length compared to nonsmokers [15]. Furthermore, Kim et al. [16] reported that smoking OSA patients presented thicker lamina propria of the uvula(More)
OBJECTIVE To explore the correlation between intermittent hypoxia (IH)-induced apoptosis of human umbilical vein endothelial cells (HUVECs) and release of cytochrome C (cytC) from mitochondria. METHODS HUVECs in IH groups were exposed to repetitive cycles (1% O2 5 min alternating with 21% O2 5 min, 37 ℃, 5% CO2) for different exposure time (8, 16 and 24(More)
Serotonergic neurons play key roles in various biological processes. However, circuit mechanisms underlying tight control of serotonergic neurons remain largely unknown. Here, we systematically investigated the organization of long-range synaptic inputs to serotonergic neurons and GABAergic neurons in the dorsal raphe nucleus (DRN) of mice with a(More)