Li Zhi-Heng

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BACKGROUND Wilms tumor (WT) is an embryonic kidney cancer, for which histone acetylation might be a therapeutic target. LBH589, a novel targeted agent, suppresses histone deacetylases in many tumors. This study investigated the antitumor activity of LBH589 in SK-NEP-1 and G401 cells. METHODS SK-NEP-1 and G401 cell growth was assessed by CCK-8 and in nude(More)
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