Share This Author
Asymmetric Catalytic Meerwein–Ponndorf–Verley Reduction of Ketones with Aluminum(III)-VANOL Catalysts
We report herein an efficient aluminum-catalyzed asymmetric MPV reduction of ketones with broad substrate scope and excellent yields and enantiomeric inductions. A variety of aromatic (both electro...
Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage
- Chunling Yuan, Chunmei Dai, Ziqiang Li, Li Zheng, Miaoxin Zhao, Sumin Dong
- Biology, PsychologyNeurochemical Research
- 13 March 2020
It is possible that Bex reversed depression-like behaviour in mice by reducing neuroinflammation and protecting against synaptic damage induced by LPS or CORT, and rescued the decrease in the expression of BDNF, and inhibition of CREB/BDNF/ERK pathway, in CORT-induced mice.
Synthesis of Tripeptide Derivatives with Three Stereogenic Centers and Chiral Recognition Probed by Tetraaza Macrocyclic Chiral Solvating Agents Derived from d-Phenylalanine and (1 S,2…
Results indicate that enantiomers of (±)-G1-G9 can be effectively discriminated in the presence of TAMCSAs 1a-1d by 1H NMR signals of multiple protons exhibiting nonequivalent chemical shifts.
Multicomponent Catalytic Asymmetric Synthesis of trans-Aziridines.
- Yubai Zhou, A. Gupta, Munmun Mukherjee, Li Zheng, W. Wulff
- ChemistryThe Journal of organic chemistry
- 27 November 2017
A multicomponent trans-aziridination of aldehydes, amines, and diazo compounds with BOROX catalysts is developed and was tolerant of a number of functional groups including ethers, esters, epoxides, carbamates, and phthalimides.
Synthesis of Ag modified vanadium oxide nanotubes and their antibacterial properties
Cu(II)-Catalyzed Homocouplings of (Hetero)Arylboronic Acids with the Assistance of 2-O-Methyl-d-Glucopyranose
This is the first report of a natural ligand improving the copper-catalyzed homocouplings of (hetero)arylboronic acids and in situ React IR technology was used to confirm the effectivity of this catalyst system.
The Resolution of Vaulted Biaryl Ligands via Borate Esters of Quinine and Quinidine.
- Xiaopeng Yin, Li Zheng, Aliakbar Mohammadlou, Brian Reese Cagnon, W. Wulff
- Chemistry, BiologyThe Journal of organic chemistry
- 20 July 2020
Proof of principle has been demonstrated for the dynamic thermodynamic resolution of the vaulted biaryl ligands with this method in combination with a non-chiral copper(II) complex that can racemize the ligand.
Syntheses,Structure and SAR Study on Sulfonylurea Compounds(III) ──Crystal and Molecular Structure of N-[2'-(4,6-dimethyl)pyrimidinyl]-2-ethyl Carboxylate-benzene Sulfonylurea
Synthesis and crystal structure of title molecule was reported here. This crystal consists of title molecules with solvent molecules CH2C12. It is triclinic, belonging to space group P1 with unit…
Synthesis and Biological Activity of Pyrazole Derivatives
- Li Zheng
Thirty new pyrazole acylhydrazine derivatives containing carboxylate,sulfonylate, hydrazone and dipyrazole ketone were synthesized from the intermediate 1, 3,4-substituted-5-pyrazole carboxylic…
α-d-Galacturonic Acid as Natural Ligand for Selective Copper-Catalyzed N-Arylation of N-Containing Heterocycles
The first application of α-d-galacturonic acid hydrate (GalA) is reported here, as a potential O-donor ligand, which allows rapid access to several pharmaceutical intermediates and can be easily transformed into a variety of other interesting scaffolds as well.