Li-Yun Yang

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Yi Liu2
Ye-Zhong Zhang1
Xun-Jin Zhu1
Li-Li Yuan1
2Yi Liu
1Ye-Zhong Zhang
1Xun-Jin Zhu
1Li-Li Yuan
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Mitochondria have recently emerged as novel targets for cancer therapy due to its important roles in fundamental cellular function. Discovery of new chemotherapeutic agents that allow for simultaneous treatment and visualization of cancer is urgent. Herein, we demonstrate a novel bifunctional mitochondria-targeted anticancer agent (FPB), exhibiting both(More)
In this work, fluorescence spectroscopy in combination with circular dichroism spectroscopy and molecular modeling was employed to investigate the binding of 10-hydroxycamptothecin (HCPT) to human serum albumin (HSA) under simulative physiological conditions. The experiment results showed that the fluorescence quenching of HSA by HCPT was a result of the(More)
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