Li-Yun Fu

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BACKGROUND Housekeeping genes are routinely used as endogenous references to account for experimental differences in gene expression assays. However, recent reports show that they could be de-regulated in different diseases, model animals, or even under varied experimental conditions, which may lead to unreliable results and consequently misinterpretations.(More)
PURPOSE To evaluate the prognostic value of preoperative plasma osteopontin (OPN) levels in patients with early stage of hepatocellular carcinoma (HCC). METHODS Preoperative plasma levels of OPN were detected by ELISA in 68 patients with tumor-node metastasis system stage-I of HBV-related HCC, and their association with tumor recurrence or patients'(More)
OBJECTIVE To identify the metastasis-related miRNAs in hepatocellular carcinoma (HCC) cell lines. METHODS A qRT-PCR method was established and optimized. RESULTS All candidate metastasis associated miRNAs except miR-124a were expressed in high metastasis cell line MHCC97H and low metastasis cell line MHCC97L, while some miRNAs were differentially(More)
Epidermal growth factor (EGF) and its signaling molecules, EGFreceptor (EGFR) and signal transducer and activator of transcription factor 3 (STAT3), have been considered to play a role in liver fibrosis and cirrhosis. Plumbagin (PL) is an extracted component from the plant and has been used to treat different kinds of cancer. However, its role in regulation(More)
INTRODUCTION Modern underground coal mining requires certainty about geological faults and other structural features for safety reasons. Even a fault with a throw of a few metres can create safety issues and lead to costly delays in mine production. To ensure there are no unwelcome surprises concerning seam conditions during mining, seismic reflection(More)
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