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The aim of the present study was to investigate the effects of minocycline on cognitive functions in neonatal rat after hypoxia exposure and the underlying mechanism. A model of hypoxic brain damage (HBD) was developed by exposing postnatal 1 day (P1) rats to systemic hypoxia. The rats were intraperitoneally injected with normal saline (Hy group) or(More)
The effect of a kappa-receptor agonist U-50, 488H on urine flow and the activity of TH-IR (tyrosine hydroxylase-immunoreactivity) neurons in PVH (Paraventricular neucleus of the hypothalamus) was studied in ethanol-anesthetized rats. U-50, 488H (5 micrograms/1 microliter) injected into PVH induced a potent diuretic response with no significant action on(More)
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