Li-Xiang Chen

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Whole-cell patch-clamp recordings were made from neurons in the rat's dorsal nucleus of the lateral lemniscus (DNLL) in a brain slice preparation. Planes of section were chosen to preserve the integrity of fibers in the commissure of Probst (CP) and postsynaptic responses were evoked by electrical stimulation along its length. Results showed that the(More)
This work was designed to observe the effects of nociceptin(13-17), one of the main metabolites of nociceptin (also termed orphanin FQ), in pain modulation at supraspinal level in mice. Intracerebroventricular (i.c.v.) administration of nociceptin/orphanin FQ(13-17) (N/OFQ(13-17)) (5, 0.5, 0.05, 0.005 nmol/mouse) dose-dependently induced potent hyperalgesic(More)
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