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Understanding how topics evolve in text data is an important and challenging task. Although much work has been devoted to topic analysis, the study of topic evolution has largely been limited to individual topics. In this paper, we introduce TextFlow, a seamless integration of visualization and topic mining techniques, for analyzing various evolution(More)
In this paper, we present a novel exploratory visual analytic system called TIARA (Text Insight via Automated Responsive Analytics), which combines text analytics and interactive visualization to help users explore and analyze large collections of text. Given a collection of documents, TIARA first uses topic analysis techniques to summarize the documents(More)
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This paper shows that different " meta-model-checking " analyses can be conducted efficiently on a generic data structure we call a support set. Support sets may be viewed as abstract encodings of the " evidence " a model checker uses to justify the yes/no answers it computes. We indicate how model checkers may be modified to compute supports sets without(More)
  • Nicolas Dzamko, Francisco Inesta-Vaquera, Jiazhen Zhang, Chengsong Xie, Huaibin Cai, Simon Arthur +7 others
  • 2012
Mutations in leucine-rich repeat kinase 2 (LRRK2) are strongly associated with late-onset autosomal dominant Parkinson's disease. LRRK2 is highly expressed in immune cells and recent work points towards a link between LRRK2 and innate immunity. Here we demonstrate that stimulation of the Toll-Like Receptor (TLR) pathway by MyD88-dependent agonists in bone(More)
BACKGROUND All-trans retinoic acid (RA) is one of the most important morphogens with pleiotropic actions. Its embryonic distribution correlates with neural differentiation in the developing central nervous system. To explore the precise effects of RA on neural differentiation of mouse embryonic stem cells (ESCs), we detected expression of RA nuclear(More)
  • Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser +25 others
  • 2012
DNA methylation at the 5 position of cytosine (5-mC) is a key epigenetic mark that is critical for various biological and pathological processes. 5-mC can be converted to 5-hydroxymethylcytosine (5-hmC) by the ten-eleven translocation (TET) family of DNA hydroxylases. Here, we report that "loss of 5-hmC" is an epigenetic hallmark of melanoma, with(More)
Text visualization becomes an increasingly more important research topic as the need to understand massive-scale textual information is proven to be imperative for many people and businesses. However, it is still very challenging to design effective visual metaphors to represent large corpora of text due to the unstruc-tured and high-dimensional nature of(More)