• Publications
  • Influence
FSH Directly Regulates Bone Mass
Postmenopausal osteoporosis, a global public health problem, has for decades been attributed solely to declining estrogen levels. Although FSH levels rise sharply in parallel, a direct effect of FSHExpand
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A Selective and Oral Small Molecule Inhibitor of Vascular Epithelial Growth Factor Receptor (VEGFR)-2 and VEGFR-1 Inhibits Neovascularization and Vascular Permeability
Vascular endothelial growth factor (VEGF) is a key driver of the neovascularization and vascular permeability that leads to the loss of visual acuity in diabetic retinopathy and neovascularExpand
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Mode of Action of Interleukin-6 on Mature Osteoclasts. Novel Interactions with Extracellular Ca2+ Sensing in the Regulation of Osteoclastic Bone Resorption
We describe a physiologically significant mechanism through which interleukin-6 (IL-6) and a rising ambient Ca2+ interact to regulate osteoclastic bone resorption. VOXEL-based confocal microscopy ofExpand
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Quercetin Induces Rapid eNOS Phosphorylation and Vasodilation by an Akt-Independent and PKA-Dependent Mechanism
Consumption of the flavonoid quercetin exerts beneficial effects on many chronic diseases. The mechanisms involved in the vasorelaxant effect of quercetin remain uncertain. In the present study, weExpand
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2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside ameliorates vascular senescence and improves blood flow involving a mechanism of p53 deacetylation.
BACKGROUND AND AIMS 2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside (THSG), a resveratrol analog with glucoside, has been shown in various studies to inhibit proliferation of vascular smooth muscleExpand
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Regulation of drug sensitivity of gastric cancer cells by human calcyclin-binding protein (CacyBP)
BackgroundCalcyclin-binding protein (CacyBP) was previously identified as an upregulated gene in a multidrug-resistant gastric cancer cell line, SGC7901/ADR, compared to its parental cells, SGC7901,Expand
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Heroin Use Promotes HCV Infection and Dysregulates HCV-Related Circulating microRNAs
  • Y. Zhou, Li Sun, +10 authors W. Ho
  • Biology, Medicine
  • Journal of Neuroimmune Pharmacology
  • 9 January 2015
Hepatitis C virus (HCV) infection is common among injection drug users (IDUs). There is accumulating evidence that circulating microRNAs (miRNAs) are associated with HCV infection and diseaseExpand
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Inhibitory effect of biosynthetic nanoscale peptide Melittin on hepatocellular carcinoma, driven by survivin promoter.
  • L. Qu, M. Jiang, +6 authors Jin Si
  • Medicine, Materials Science
  • Journal of biomedical nanotechnology
  • 1 April 2014
Hepatic resection and orthotopic liver transplantation are the only potentially curative treatments for hepatocellular carcinoma (HCC) but are indicated only in a minority of patients. BiosyntheticExpand
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The combined effects of celecoxib and minocycline hydrochloride on inhibiting the osseous metastasis of breast cancer in nude mice.
Breast carcinomas show a trend toward bone metastasis that is prevalent worldwide. Celecoxib (CX) and minocycline hydrochloride (MH) have both been widely used in treating breast cancer; however,Expand
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Osteoblasts response to allogenic and xenogenic solvent dehydrated cancellous bone in vitro.
The present in vitro study investigates the cellular interaction of primary human osteoblasts with human and bovine solvent dehydrated cancellous bone (SDCB) discs. These are bio-implants fromExpand
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