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Lighter is a fast, memory-efficient tool for correcting sequencing errors. Lighter avoids counting k-mers. Instead, it uses a pair of Bloom filters, one holding a sample of the input k-mers and the other holding k-mers likely to be correct. As long as the sampling fraction is adjusted in inverse proportion to the depth of sequencing, Bloom filter size can(More)
Increasing evidences indicate the concurrence and interrelationship of depression and cognitive impairments. The present study was undertaken to investigate the effects of two depressive animal models, learned helplessness (LH) and chronic mild stress (CMS), on the cognitive functions of mice in the Morris water maze task. Our results demonstrated that both(More)
Lighter is a fast, memory-efficient tool for correcting sequencing errors. Lighter avoids counting k-mers. Instead, it uses a pair of Bloom filters, one holding a sample of the input k-mers and the other holding k-mers likely to be correct. As long as the sampling fraction is adjusted in inverse proportion to the depth of sequencing, Bloom filter size can(More)
Accumulating evidence has implicated neuropeptides in modulating recognition, learning and memory. However, to date, no study has investigated the effects of neuropeptide Trefoil factor 3 (TFF3) on the process of learning and memory. In the present study, we evaluated the acute effects of TFF3 administration (0.1 and 0.5mg/kg, i.p.) on the acquisition and(More)
Adversity, particularly in early life, can cause illness. Clues to the responsible mechanisms may lie with the discovery of molecular signatures of stress, some of which include alterations to an individual's somatic genome. Here, using genome sequences from 11,670 women, we observed a highly significant association between a stress-related disease, major(More)
High Efficiency Video Coding (HEVC), the latest international standard of video coding under development, has shown a major breakthrough with regards to compression efficiency. But most of the currently published studies were intended to evaluate the overall R-D performance of HEVC in comparison to prior H.264/AVC video coding standard. In this paper, we(More)
We propose a watermarking scheme for color images based on local quaternion Fourier spectral analysis (LQFSA).The merits of the proposed scheme include: 1) Quaternion Fourier transform is defined in a 4D vector space and thus provides a larger embedding scope for watermark than conventional monochannel transformation techniques. 2) We improve the(More)
Community discovery is one of the most important steps to understand the social networks. We propose a hierarchical diffusion method to detect the community structure. Our algorithm is based on the idea that people in different communities usually share less common friends. We also make use of the fact that people usually make decisions based(More)