Li-Shuang Zhu

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BACKGROUND AND OBJECTIVES Vascular endothelial growth factor (VEGF) has been shown to play an important role in the development and progress of diabetic retinopathy (DR). A number of case-control studies focused on the association between VEGF -2578C/A and risk for DR. But the results were not always consistent, so we performed a meta-analysis to evaluate(More)
PURPOSE OF THE STUDY Cytotoxic-T lymphocyte antigen-4 (CTLA-4) has been shown to play an important role in the development and progression of thyroid associated ophthalmopathy (TAO). A number of case-control studies focused on the association between CTLA-4 +49A/G polymorphism and risk for TAO. But the results were not always consistent. So we performed a(More)
The aim of this study was to detect the effect of the CD40 ligand (CD40L) on the expression of vascular cell adhesion molecule 1 (VCAM-1) and E-Selectin in orbital fibroblasts (OFs) from patients with Graves’ orbitopathy (GO), as well as the signaling pathways involved in this effect. OFs were isolated from orbital tissues obtained from patients with severe(More)
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