Li-Rong Wang

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OBJECTIVE To evaluate the association between single nucleotide polymorphisms (SNPs) of cytotoxic T-lymphocyte-associated protein 4 (CTLA4) gene and susceptibility to cervical cancer. METHODS One hundred patients and 100 healthy controls from Hubei province were genotyped for 20 polymorphic loci using Sequenom. RESULTS The frequency of rs11571316 G(More)
Peach (Prunus persica (L.) Batsch) is one of the most important model fruits in the Rosaceae family. Native to the west of China, where peach has been domesticated for more than 4,000 years, its cultivation spread from China to Persia, Mediterranean countries and to America. Chinese peach has had a major impact on international peach breeding programs due(More)
Single-walled carbon nanotubes (SWCNTs) are broadly used for various biomedical applications such as drug delivery, in vivo imaging, and cancer photothermal therapy due to their unique physiochemical properties. However, once they enter the cells, the effects of SWCNTs on the intracellular organelles and macromolecules are not comprehensively understood.(More)
Peach was domesticated in China more than four millennia ago and from there it spread world-wide. Since the middle of the last century, peach breeding programs have been very dynamic generating hundreds of new commercial varieties, however, in most cases such varieties derive from a limited collection of parental lines (founders). This is one reason for the(More)
This paper proposes a well-structured modified Booth encoding (MBE) multiplier architecture. The design adopts an improved Booth encoder and selector to achieve an extra-row- removal and a hybrid spare-tree approach to design two's complementation circuit to both reduce the area and improve the speed. Experimental results on a 32 bit multiplier show that it(More)
Defective autophagy in Alzheimer's disease (AD) promotes disease progression in diverse ways. Here, we demonstrate impaired autophagy flux in primary glial cells derived from CRND8 mice that overexpress mutant amyloid precursor protein (APP). Functionalized single-walled carbon nanotubes (SWNT) restored normal autophagy by reversing abnormal activation of(More)
Researchers conducted a study in a Taiwanese medical center from June 2009 to June 2011 to investigate the relations of perceived stress and lifestyle to breast cancer. A total of 157 cases and 314 controls completed a structured questionnaire. Using multiple logistic regression models, high perceived stress (adjusted odds ratio [AOR] = 1.65; 95% confidence(More)
A gene, presumably involved in spermatogenesis, was identified and characterized by using cDNA microarray. Hybridization intensity was 2.13 fold higher in adult testis than that in fetal testis. The full length of this gene was 4288 bp and it encoded a 578 amino acid protein. Conserved structure and amino acid sequence analysis revealed that the protein(More)
Prenatal stress results in various learning, behavioral and emotional alterations observed in later life. However, the mechanisms underlying these effects of prenatal stress are not fully understood. In the present study we examined the impact of prenatal stress (an unpredictable restraint stress) during gestational days 13 to 20 on the performance in(More)
The duration of protection of hepatitis B vaccine remains incompletely understood. To assess the long-term protection provided by a primary vaccine series, the current study again recruited all subjects of a previous randomized placebo-controlled trial cohort 23 years after vaccination. Two hundred and sixty-one healthy children aged 5-9 years living in a(More)