Li-Ran Zhu

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OBJECTIVE To study the preventive and therapeutic effects of total saponin of Dioscorea (TSD) on chronic hyperuricemia, and its effect on urate transporter 1 (URAT1) in rats. METHOD Ninety male rats were randomly divided into 6 groups: the normal group, the model group, TSD high-, medium- and low-dose (300, 100, 30 mg x kg(-1)) groups and the(More)
Interleukin-1b (IL-1b) and tumor necrosis factor-a (TNF-a) synergistically induce and sustain arthritis. Two competing hypotheses of arthritis induction are 1) that TNF preferentially mediates inflammation, whereas IL-1 impels bone destruction, or 2) that either cytokine controls the entire process. In this study, these propositions were tested in two(More)
UNLABELLED The effects of unilateral truncal vagotomy (UTV) and bilateral truncal vagotomy (BTV) on antrum EC cells, G cells and oxyntic gland area argyrophil cells were studied in rats by using immunohistochemistry processes, Grimelius argyrophil stain and microscopic image analysis technique. RESULTS (1) In UTV animals, two weeks postoperation, the(More)
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