Li-Nan Xu

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UCN-01 (7-hydroxystaurosporine), a protein kinase inhibitor, has attracted a great deal of attention as a potent antitumour agent. Several clinical trials of UCN-01 alone or in combination with other agents for different tumour types are currently underway, and some of these trials have had positive results. Hepatocellular carcinoma has high incidence rates(More)
Genetic screens using Saccharomyces cerevisiae have identified an array of cytosolic Hsp70 mutants that are impaired in the ability to propagate the yeast [PSI(+)] prion. The best characterized of these mutants is the Ssa1 L483W mutant (so-called SSA1-21), which is located in the substrate-binding domain of the protein. However, biochemical analysis of some(More)
To observe the effect of gene expression and tumorigenicity in hybrid cells of human embryonic stem cells (hESCs) and ovarian cancer cells in vitro and in vivo using a mouse model, and to determine its feasibility in reprogramming tumour cells growth and apoptosis, for a potential exploration of the role of hESCs and tumour cells fusion in the management of(More)
After publication of this work [1], we noted that we inadvertently failed to include the complete list of all co-authors. In addition, it has been brought to our attention that an Authors Contributions section was not included in the published article. In this correction we rectify these mistakes. The full list of authors and the Authors Contributions(More)
After publication of this work [1], we noted that we inadvertently failed to include the complete list of all co-authors. In addition, it has been brought to our attention that an Authors Contributions section was not included in the published article. In this correction we rectify these mistakes. The full list of authors and the Authors Contributions(More)
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