Li - Ming Cao

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For testing average bioequivalence, a simple test that improves upon the two-one sided test (TOST) is derived. The new test uses a critical value that is a non-increasing continuous function of the sample standard deviation, and the function is numerically obtained. Simulation results show that the resulting test performs well in terms of type I error(More)
This paper addresses hypothesis testing problems concerning the subject-by-formulation interaction matrix for the assessment of multivariate bioequivalence. Two problems are addressed: (a) the problem of testing if the subject-by-formulation interaction matrix itself is zero, and (b) the problem of testing if suitable scalar valued functions of the(More)
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