Li Lian Sheng

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Haplotypes are specially important in the study of complex diseases since they contain more information about gene alleles than genotype data. However , getting haplotype data via experiments methods is techniquely difficult and expensive. Thus, haplotype inference through computational methods is practical and attractive. There are several models for(More)
To clarify the antinociceptive mechanism of acupuncture on acute pain, c-fos protein (Fos) expression induced by tooth pulp stimulation was immunohistochemically examined in the spinal trigeminal subnucleus pars caudalis (spVc) and the periaqueductal gray (PAG) of rats with or without Neiting acupuncture. The central projection of trigeminal ganglion(More)
IL-10-producing B cells (B10 cells) have been shown to play a suppressive role in the peripheral blood of humans, with their numbers and function altered in several autoimmune diseases. However, the role of B10 cells in Graves' disease (GD) remains unknown. In this study, we demonstrated that B10 cells in human peripheral blood belonged to a CD24(hi)CD27(+)(More)
OBJECTIVE To investigate the association of serum osteocalcin with carotid atherosclerosis in patients with type 2 diabetes. METHODS We performed a cross-sectional community-based study in metropolitan area. Serum total osteocalcin was measured by radioimmunoassay in 382 men and 435 postmenopausal women. The carotid artery intima-media thickness (IMT) and(More)
The potassium voltage-gated channel, KQT-like subfamily member 1 (KCNQ1) is a member of 11 mammalian Kv channel families that plays a key role for the repolarization of the cardiac action potential as well as water and salt transport. Genome-wide association studies have identified KCNQ1 as a type 2 diabetes (T2D) susceptibility gene in populations of Asian(More)
Aimed at the stabilization problem of the Inertia Wheel Pendulum system, a recursive design method of stabilization controller is present. And a state feedback controller with explicit form was obtained. The stability of the closed loop system was analyzed by input-to-state stability. Finally, the effectiveness and performance of the proposed stabilization(More)
Packed forest chart parser, like the traditional chart parsing algorithm, uses charts to store all the information produced while parsing to avoid redundant works. Its advantage over the traditional chart parser was the packed forest representation. The algorithm not only shares the non-terminal categories as what was done in the shared parse forest, but(More)
This study develops an integrated model to investigate the economic and environmental effects of a unilateral maritime emission regulation vis-à-vis a uniform maritime emission regulation. The proposed model explicitly incorporates the effects of competition between regional ports and between shipping companies, and captures operational considerations such(More)
Background. This study investigated an association between systemic absolute neutrophil count (ANC) and albuminuria in elderly Chinese people. Methods. A cross-sectional study was conducted on 2265 participants attending a routine medical examination in Minhang District as part of a Platform of Chronic Disease program. Their drug history, waist(More)