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STUDY QUESTION What is the value of a new strategy for preimplantation genetic diagnosis (PGD) of monogenic diseases: blastocyst biopsy, cryopreservation and thawed embryo transfer? SUMMARY ANSWER This strategy is highly effective for PGD of monogenic diseases and merits wide use. WHAT IS KNOWN ALREADY PGD of monogenic diseases is conventionally(More)
Preimplantation genetic diagnosis (PGD) is gradually widely used in prevention of gene diseases and chromosomal abnormalities. Much improvement has been achieved in biopsy technique and molecular diagnosis. Blastocyst biopsy can increase diagnostic accuracy and reduce allele dropout. It is cost-effective and currently plays an important role. Whole genome(More)
Soft error is one critical issue faced by nano-scale random access memories (RAMs). Three-dimensional (3D) RAM with through-silicon via (TSV) is a new approach for overcoming the memory wall. A 3D RAM consists of multiple dies vertically stacked. Therefore, the upper die provides the shielding effect for the lower die. Thus, the SER in the upper die is(More)
Most in vitro fertilization (IVF) experts and infertility patients agree that the most ideal assisted reproductive technology (ART) outcome is to have a healthy, full-term singleton born. To this end, the most reliable policy is the single-embryo transfer (SET). However, unsatisfactory results in IVF may result from plenty of factors, in which aneuploidy(More)
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