Li-Juan Wang

Xiao-Dong Pan2
Sheng-Jia Shi2
Chang-Chun Ruan2
Yi-Nan Zheng2
2Xiao-Dong Pan
2Sheng-Jia Shi
2Chang-Chun Ruan
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Trastuzumab resistance is leading cause of mortality in HER2-positive breast cancers, and the role of TGF-β-induced epithelial-mesenchymal transition (EMT) in trastuzumab resistance is well established, but the involvement of lncRNAs in trastuzumab resistance is still unknown. Here, we generated trastuzumab-resistant breast cancer cells with increased(More)
Intrahepatic cholangiocarcinoma (ICC) constitutes the second-most common primary hepatic malignancy. MicroRNAs (miRNAs) play important roles in the pathogenesis of ICC. However, the clinical significance of miR-21 levels in ICC remains unclear. Here, we investigated the role of miR-21 in ICC and found that its expression was significantly upregulated in(More)
  • Guo-Fen Qiao, Zhao Qian, Hong-Li Sun, Wen-Xiao Xu, Zhen-Yu Yan, Yang Liu +5 others
  • 2013
Hyperpolarization-activated currents (Ih) mediated by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels modulate excitability of myelinated A- and Ah-type visceral ganglion neurons (VGN). Whether alterations in Ih underlie the previously reported reduction of excitability of myelinated Ah-type VGNs following ovariectomy (OVX) has remained(More)
BACKGROUND The coverage of HIV testing among Chinese men who have sex with men (MSM) remains low after the scale-up of free HIV testing at government-sponsored testing sites. We evaluated the feasibility of home-based HIV self-testing and the willingness to be HIV tested at community-based organizations (CBO). METHODS We recruited MSM via on-line(More)
Rhodococcus sp. Chr-9 can degrade pyridine in the presence of chromate. Its draft genome sequence revealed that strain Chr-9 harbors sets of genes for resistance to heavy metals such as lead, mercury, arsenate, and cobalt, as well as three different gene clusters for metabolizing aromatic compounds, such as phenol, benzoate, and 4-nitrophenol.
OBJECTIVE To explore the association between the three polymorphisms [ C825T, C1429T and G(-350)A] of the gene encoding the G protein beta 3 subunit (GNB3) and hypertension by performing a case-control study in the northern Han Chinese population. METHODS We recruited 731 hypertensive patients and 673 control subjects (the calculated power value was >(More)
A method to improve the growth repeatability of low-density InAs/GaAs self-assembled quantum dots by molecular beam epitaxy is reported. A sacrificed InAs layer was deposited firstly to determine in situ the accurate parameters of two- to three-dimensional transitions by observation of reflection high-energy electron diffraction patterns, and then the InAs(More)
A new saponin, malonylginsenoside Ra3, was isolated from the fresh root of Panax ginseng, along with four known ginsenosides. The new compound was identified as (20S)-protopanaxadiol-3-O-(6-O-malonyl-beta-D-glucopyranosyl(1-->2)-beta-D-glucopyranoside-20-O-beta-D-xylopyranosyl(1-->3)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranoside on the basis of(More)
A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-alpha-L-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside] (2), from the dried roots of Rubia cordifolia. Their structures were elucidated on the(More)