Learn More
Aromatic amines, N-nitroso compounds and heterocyclic amines are suspected human pancreatic carcinogens. Cytochrome P450 (CYP) 1A2, N-acetyltransferase (NAT) 1, NAT2 and sulfotransferase (SULT) are enzymes involved in the metabolism of these carcinogens. To test the hypothesis that genetic variations in carcinogen metabolism modify the risk of pancreatic(More)
This paper concerns two important techniques, characterization and property-preserving transformation , for verifying some basic properties of asymmetric choice Petri nets (AC nets). In the literature, a majority of the characterizations are for ordinary free choice nets. This paper presents many extended (from free choice nets) and new characterizations(More)
Four loci have been associated with pancreatic cancer through genome-wide association studies (GWAS). Pathway-based analysis of GWAS data is a complementary approach to identify groups of genes or biological pathways enriched with disease-associated single-nucleotide polymorphisms (SNPs) whose individual effect sizes may be too small to be detected by(More)
An increasing number of circulating micro-ribonucleic acids (microRNAs, miRNAs) have been discovered its potential as biomarkers to diagnose neurodegenerative diseases (NDs) by many researchers. However, there were obvious inconsistencies among previous studies, and thus we performed this meta-analysis to evaluate whether miRNA is an effective biomarker(More)
The literature has consistently reported no association between low to moderate alcohol consumption and pancreatic cancer; however, a few studies have shown that high levels of intake may increase risk. Most single studies have limited power to detect associations even in the highest alcohol intake categories or to examine associations by alcohol type. We(More)
As more and more P2P applications being popular in Inter-net, one of important problem to be solved is inspiring users to cooperate each other actively and honestly, the reputation mechanism which is a hot spot for P2P research has been proposed to conquer it. Because of the characters of virtuality and anonymous in the network, it is very easy for users(More)
The reach ability tree for an unbounded net system is infinite. By using $\omega$ symbol to represent infinitely many markings, cover ability tree can provide a finite form. However, with too much information lost, it can not check properties such as reach ability, deadlock freedom, liveness, etc. In this paper, an improved reachability tree (IRT for short)(More)
Genetic variation in DNA repair may affect the clinical response to cytotoxic therapies. We investigated the effect of six single nucleotide polymorphisms of the RecQ1, RAD54L, XRCC2, and XRCC3 genes on overall survival of 378 patients with pancreatic adenocarcinoma who were treated at University of Texas M.D. determined using the MassCode method. Survival(More)