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Olfactory ensheathing cells (OECs) are a unique type of macroglia with axonal growth-promoting properties. The migrating ability of OECs in CNS is essential for neural regeneration. However, little is known about the extracellular and intracellular factors that regulate OEC migration. In the present study, we examined the effects of glial cell line-derived(More)
TrkA receptor signaling is essential for nerve growth factor (NGF)-induced survival and differentiation of sensory neurons. To identify possible effectors or regulators of TrkA signaling, yeast two-hybrid screening was performed using the intracellular domain of TrkA as bait. We identified muc18-1-interacting protein 2 (Mint2) as a novel TrkA-binding(More)
This paper concerns two important techniques, characterization and property-preserving transformation , for verifying some basic properties of asymmetric choice Petri nets (AC nets). In the literature, a majority of the characterizations are for ordinary free choice nets. This paper presents many extended (from free choice nets) and new characterizations(More)
RET receptor signalling is essential for glial-cell-line-derived neurotrophic factor (GDNF)-induced survival and differentiation of various neurons such as mesencephalic neurons. To identify proteins that mediate RET-dependent signaling, yeast two-hybrid screening was performed with the intracellular domain of RET as bait. We identified a new interaction(More)
An increasing number of circulating micro-ribonucleic acids (microRNAs, miRNAs) have been discovered its potential as biomarkers to diagnose neurodegenerative diseases (NDs) by many researchers. However, there were obvious inconsistencies among previous studies, and thus we performed this meta-analysis to evaluate whether miRNA is an effective biomarker(More)
As more and more P2P applications being popular in Inter-net, one of important problem to be solved is inspiring users to cooperate each other actively and honestly, the reputation mechanism which is a hot spot for P2P research has been proposed to conquer it. Because of the characters of virtuality and anonymous in the network, it is very easy for users(More)