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High expression of long non-coding RNA lncRNA-ATB is correlated with metastases and promotes cell migration and invasion in renal cell carcinoma.
- J. Xiong, Y. Liu, Li Jiang, Yang Zeng, Wei Tang
- Biology, Medicine
- Japanese journal of clinical oncology
- 1 April 2016
It is found that long non-coding ribonucleic acid activated by transforming growth factor β knockdown could inhibit cell proliferation, trigger apoptosis, reduce epithelial-to-mesenchymal transition program, and suppress cell migration and invasion during renal cell carcinoma metastasis. Expand
Amide-linked local anesthetics induce apoptosis in human non-small cell lung cancer.
- Hong-wei Wang, Le-yi Wang, Li Jiang, Summing Tian, T. Zhong, X. Fang
- Biology, Medicine
- Journal of thoracic disease
- 31 October 2016
The cytotoxic effect of amide-linked local anesthetics on NSCLC cells were mainly due to apoptosis, and the antitumor mechanism of lidocaine and ropivacaine may involve apoptotic pathways and MAPK pathways. Expand
Overexpression of Id-1 protein is a marker in colorectal cancer progression.
- Zeng-ren Zhao, Zhi‐Yong Zhang, Hong Zhang, Li Jiang, Ming-Wei Wang, Xiao-Feng Sun
- Oncology reports
- 1 February 2008
The inhibitor of differentiation/DNA binding 1 (Id-1), a negative regulator of basic helix-loop-helix transcription factors, plays an important role in the regulation of cell proliferation and… Expand
CD30 expression is a novel prognostic indicator in extranodal natural killer/T-cell lymphoma, nasal type
It is shown that expression of CD30 was not related to response to treatment but was an independent prognostic factor for both OS and PFS in ENKTL, nasal type, which suggests a role for CD30 in the pathogenesis of this disease and may support the incorporation of anti-CD30-targeted therapy into the treatment paradigm for ENkTL. Expand
Development of an autophagy-related gene expression signature for prognosis prediction in prostate cancer patients
The authors' ARGs based prediction models are a reliable prognostic and predictive tool for overall survival and disease-free survival in prostate cancer patients. Expand
A comparative proteomic study to characterize the vinblastine resistance in human ovarian cancer cells
- Dawn P. G. Brown, Y. Gökmen-Polar, +7 authors Mu Wang
- Biology, Medicine
- Proteomics. Clinical applications
This study demonstrates a novel understanding of the mechanism of drug resistance and provides a valuable resource for future studies on drug resistance to vinblastine and represents a good example of how to increase the protein dynamic range and reduce sample complexity using currently available tools. Expand
[Down-regulation of GRP78 Enhances Chemotherapy Sensitivity to VP-16 in Lung Adenocarcinoma.].
- Li Jiang, Lichuan Zhang, Qi Wang, Siyan Wang
- Zhongguo fei ai za zhi = Chinese journal of lung…
- 20 November 2009
BAPTA-AM is highly effective in the inhibition of GRp78, down-regulation of GRP78 can significantly increase the sensitivity of adenocacinoma lung cancer to VP-16, and inhibition of the expression ofGRP78 by chemicals such as BAPta-AM or anti-sense RNA may be a new therapeutic strategies to lung cancer. Expand
Upregulation of GRP78 and GRP94 and Its Function in Chemotherapy Resistance to VP-16 in Human Lung Cancer Cell Line SK-MES-1
The results showed that upregulation of GRP78 and GRP94 can significantly confer the chemoresistance to VP-16 in human lung cancer cell line SK-MES-1. Expand
Nup88 Expression in Normal Mucosa, Adenoma, Primary Adenocarcinoma and Lymph Node Metastasis in the Colorectum
The results suggest that Nup88 may play a role during the development, aggressiveness and differentiation of colorectal tumours. Expand
NPRL2 enhances autophagy and the resistance to Everolimus in castration‐resistant prostate cancer
The role of NPRL2 and its potential resistance to EVS in CRPC is evaluated and mTOR signaling and drug resistance in castration‐resistant prostate cancer is still unclear. Expand