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When expression of more than one gene is required in cells, bicistronic or multicistronic expression vectors have been used. Among various strategies employed to construct bicistronic or multicistronic vectors, an internal ribosomal entry site (IRES) has been widely used. Due to the large size and difference in expression levels between genes before and(More)
Remote user authentication is used to validate the legitimacy of a remote login user. Conventional user authentication schemes are suited to solve the privacy and security problems for the single client/server architecture environment. However, the use of computer networks and information technology has grown spectacularly. More and more network(More)
Conventional remote password authentication schemes allow a serviceable server to authenticate the legitimacy of a remote login user. However, these schemes are not used for multiserver architecture environments. We present a remote password authentication scheme for multiserver environments. The password authentication system is a pattern classification(More)
Recently, Peyravian and Zunic proposed a simple but efficient password authentication system. Their scheme is based on the collision-resistant hash function, such as SHA-1. Their scheme did not use any cryptosystems (such as DES, RSA, etc.). However, their scheme is vulnerable to guess attack. An attacker can easily obtain a user's password by guessing(More)
The aim of this study was to investigate the association of the thymidylate synthase (TS) and methylenetetrahydrofolate reductase (MTHFR) polymorphisms with the clinical outcomes of gastric cancer patients treated with 5-FU-based adjuvant chemotherapy. One-hundred and sixteen patients with gastric cancer were treated with 5-FU-based adjuvant chemotherapy.(More)
AIM To investigate the feasibility of detecting methylated fecal DNA as a screening tool for colorectal carcinoma (CRC) and precancerous lesions. METHODS Methylated secreted frizzled-related protein gene 2 (SFRP2), hyperplastic polyposis protein gene (HPP1) and O6-methylguanine-DNA methyltransferase gene (MGMT) in stools from 52 patients with CRC, 35(More)
BACKGROUND AND OBJECTIVE OSA is a common condition associated with cardiovascular (CV) morbidity. It remains underdiagnosed globally in part due to the limited availability and technical requirements of polysomnography (PSG). The aim of this study was to test the accuracy of two simple methods for diagnosing OSA. METHODS Consecutive subjects identified(More)
The polymorphism of p53 codon 72 (Arg72Pro) has been suggested to play an important role in many cancers and may influence the response to chemotherapy. Our aim was to investigate the association of p53 Arg72Pro polymorphism with the clinical outcome of gastric cancer patients treated with 5-FU-based adjuvant chemotherapy. The p53 codon 72 genotype was(More)