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BACKGROUND The immunohistochemical detection of estrogen (ER) and progesterone (PR) receptors in breast cancer is routinely used for prognostic and predictive testing. Whole slide digitalization supported by dedicated software tools allows quantization of the image objects (e.g. cell membrane, nuclei) and an unbiased analysis of immunostaining results.(More)
Meanwhile distributed and parallel computing has been used for medical research applications, the most recent multi-core computer architectures bring along the opportunity to adapt these paradigms to the applied medical solutions as well, thus significantly enhancing their usability. We have ported an already implemented 3D image registration algorithm to(More)
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