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BACKGROUND HIV antiretroviral therapy (ART) is often managed without routine laboratory monitoring in Africa; however, the effect of this approach is unknown. This trial investigated whether routine toxicity and efficacy monitoring of HIV-infected patients receiving ART had an important long-term effect on clinical outcomes in Africa. METHODS In this(More)
OBJECTIVE To measure nevirapine elimination in African adults undertaking a structured treatment interruption (STI) in the DART trial. DESIGN Cohort (16 women, 5 men; median weight 61 kg) within a randomized trial of management strategies. METHODS Plasma nevirapine was measured by validated high performance liquid chromatography at 0,1,2,3 and 4 weeks(More)
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