Letícia Ferreira Gontijo Silveira

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CONTEXT Loss-of-function mutations in makorin ring finger 3 (MKRN3), an imprinted gene located on the long arm of chromosome 15, have been recognized recently as a cause of familial central(More)
OBJECTIVE To investigate the role of KAL1 abnormalities in Brazilian patients with Kallmann syndrome. DESIGN In vitro experiments. SETTING Academic medical center. PATIENT(S) One hundred(More)
CONTEXT Mutations in TAC3 and TACR3 (encoding neurokinin B and its receptor) have been identified in Turkish patients with idiopathic hypogonadotropic hypogonadism (IHH), but broader populations have(More)
CONTEXT Several factors can affect adult height (AH) of patients with gonadotropin-dependent precocious puberty (GDPP) treated with depot GnRH analogs. OBJECTIVE Our objective was to determine(More)