Lester G D'Souza

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Significant survival heterogeneity exists in cystic fibrosis. Our aim was to determine whether residual function of the cystic fibrosis transmembrane conductance regulator (CFTR) is present in long-term survivors with severe mutations. Nasal potential difference (PD) and sweat chloride were measured in 34 long-term survivors (aged ≥ 40 yrs) and compared(More)
BACKGROUND Timing of surgery for ankle fractures is largely dependent on the condition of the surrounding soft-tissues. This study aimed to determine the clinical effectiveness of a pre-operative in-cast artero-venous (AV) impulse device in the management of closed ankle fractures requiring surgery. METHODS A consecutive series of 64 closed ankle(More)
The identification of the lateral cutaneous branch of the subcostal nerve supplying the anterior gluteal region while using the modified Smith-Petersen approach in performing Salter's innominate osteotomy has not been described previously. Following cadaveric dissection in six specimens and after performing routine Salter's innominate osteotomy using the(More)
INTRODUCTION In claw toe deformity, the plantar plate of the metarsophalangeal joint becomes displaced onto the dorsal aspect of the metatarsal head. The Stainsby procedure replaces the displaced plantar plate to its correct position beneath the metatarsal head. OBJECTIVE In this study we assess the efficacy of a modified Stainsby procedure for the(More)
The preferred treatment of displaced supracondylar humeral fractures in children is closed reduction and percutaneous pinning. Cross-wiring techniques are biomechanically superior to parallel lateral wiring techniques. The purpose of this study was to review the authors' experience with a novel cross-wiring technique performed entirely from the lateral(More)
INTRODUCTION The currently accepted treatment for displaced supracondylar humeral fractures in children is closed reduction and fixation with percutaneous Kirschner wires. The purpose of this study was to retrospectively review a novel cross-wiring technique where the cross-wire configuration is achieved solely from the lateral side, thereby reducing the(More)
A retrospective clinical and radiological analysis was performed on 117 patients (138 hips) with a mean age of 75 years and a mean follow-up of 11 years. The prostheses used were 2 similar monoblock femoral components with 22- and 32-mm head sizes; their effects on the wear of the high-density polyethylene cup were studied. Wear of component was determined(More)
Despite screening for congenital dislocation of the hip (CDH), children still present with a ‘late’ diagnosis of dislocation. The incidence is 0.4 to 2.0 per 1000 live births in most series (Dunn et al 1985; DHSS 1986; Bernard et al 1987). Risk factors for the development of CDH have been identified (Table I), and it has been suggested that up to 60% of(More)
The cases of two asthmatic patients who became hypokalemic after inhalation of normal doses of albuterol are presented. One patient was symptomatic and the other had only electrocardiographic changes. Both were treated successfully with oral potassium. Albuterol-induced hypokalemia and its potential cardiac toxicity are discussed briefly.
Metatarsophalangeal joint dislocations are unusual in children and usually occur in the hallux. We are reporting a case of irreducible traumatic dislocation of the fifth metatarsophalangeal joint. At open reduction, the metatarsal head was incarcerated under the flexor digitorum longus. After returning the flexor digitorum longus tendon to its anatomical(More)