Leslie Sinclair

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The present study evaluated the hypothesis that autism spectrum disorders (ASDs) are best represented as a discrete category distinct from typical behavior within autism-affected families. The latent structure, categorical versus dimensional, of ASDs informs future diagnostic revisions, clinical assessment, and the design of future research. Data were(More)
The factor structure of the Autism Diagnostic Interview-Revised (ADI-R) algorithm items was examined using exploratory (EFA) and confirmatory factor analyses (CFA) factor methods. The ADI-R was completed for 1,170 youths and adults (ages 2-46). Results of EFAs indicated strong support for two-factor structure, with social communication and stereotyped(More)
BACKGROUND The use of antipsychotic medications to treat aggression in youths with autism spectrum disorders (ASD) is based on open-label trials and efficacy studies. There are no studies examining the combined effectiveness of antipsychotic medications and intensive behavioral intervention (IBI) to treat aggression in ASD. METHODS Youths with ASD and(More)
F 1979 through 1996, dog attacks resulted in more than 300 human dog bite-related fatalities (DBRF) in the United States. Most victims were children. Studies indicate that pit bull-type dogs were involved in approximately a third of human DBRF reported during the 12-year period from 1981 through 1992, and Rottweilers were responsible for about half of human(More)
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