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Journals and Conferences
Patients with BRCA-1 and BRCA-2 germ line mutations are at an increased risk of developing pancreatic adenocarcinoma (PAC). In particular, the BRCA-2 mutation has been associated with a relative risk… (More)
Colorectal cancer in pregnancy is rare, with a reported incidence of 0.002%.1 Approximately 275 cases of colon cancer associated with pregnancy have been reported in the literature.2 A review of 205… (More)
We describe a case of melanonychia induced by PUVA. This phenomenon likely is more common than the few reports in the literature indicate.
Reduced ability to contract the quadriceps muscles is often found immediately following anterior cruciate ligament (ACL) surgery. This can lead to muscle atrophy and decreased function. Application… (More)
CONTEXT Capecitabine has shown efficacy in treatment of metastatic pancreatic cancer. Several researchers have identified thymidine phosphorylase, dihydropyrimidine dehydrogenase, or their ratio as… (More)
Therapeutic options for locally advanced pancreatic cancer (LAPC) include concurrent chemoradiation, induction chemotherapy followed by chemoradiation or systemic therapy alone. The original… (More)
4188 Introduction: Concurrent 5-FU-RT is the standard Rx for RES or LA Pan Ca. CAP is an attractive RT sensitizer due to tumor localization of thymidine phosphorylase (TP), oral administration, and… (More)
2056 Background: 5-Fluorouracil (5-FU) is an integral part of treatment of GI malignancies. While normal DPD enzyme activity is rate limiting in 5-FU catabolism, its deficiency could increase… (More)
BACKGROUND Hyopkalemia is a listed toxicity in the capecitabine (Xeloda(R); Roche, Nutley, NJ) package insert. However, the incidence and severity of this toxicity is not known. METHODS We… (More)
Will you have Y2K problems? A health system's information officer, an attorney, and two consultants share strategies for bolstering not-so-ready organizations for the new millennium.