Leslie P. Carroll

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Aerobic cultures of 207 samples of drip breast-milk from seventy mothers in hospital showed that 6 (3%) were sterile and 170 (82%) contained only the commensal organisms coagulase-negative staphylococci and Streptococcus viridans. 25 (15%) grew potential pathogens--Staphylococcus aureus in 13 (6%); enterobacteria in 15 (7%); and group-B streptococci in 3(More)
The bacteriology of 20 paired samples of breast milk was analysed to find out if discarding the first few millilitres would reduce the amount of bacterial contamination in breast milk donated to a hospital milk bank. The first sample was the initial 2-3 ml collected from the opposite breast to that first suckled by the baby, and the second was a midstream(More)
The yeast Saccharomyces cerevisiae responds to amino acid deprivation by activating a pathway conserved in eukaryotes to overcome the starvation stress. We have screened the entire yeast heterozygous deletion collection to identify strains haploinsufficient for growth in the presence of sulfometuron methyl, which causes starvation for isoleucine and valine.(More)
Drip milk can be collected in large amounts, hence its potential value for human milk banks. This advantage is however offset by its low energy value. For those milk banks which depend mostly on drip milk, the energy value of its donor milk can be improved to a more acceptable level, and total volumes of donations increased, by encouraging mothers to(More)
We developed an effective and rapid assay to detect both bio-energetic and envelope permeability (BEEP) alterations of Pseudomonas aeruginosa. The assay is based on quantification of extracellular ATP in bacterial cultures using luciferase as a reporter. To demonstrate the validity of our assay we conducted a biased screen of a transposon insertion library(More)
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