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OBJECTIVE The goal was to reduce adverse pulmonary adverse outcomes, oxidative stress, and inflammation in neonates of 24 to 28 weeks of gestation initially resuscitated with fractions of inspired oxygen of 30% or 90%. METHODS Randomized assignment to receive 30% (N = 37) or 90% (N = 41) oxygen was performed. Targeted oxygen saturation values were 75% at(More)
Oxidant stress-related mechanisms have been proposed as a major contributor to the increased prevalence of cardiovascular morbidity in adult patients with sleep-disordered breathing. Isoprostanes provide a reliable biomarker of oxidant injury in vivo. The purpose of the present study was to examine the hypothesis that oxidant stress, as evidenced by(More)
CITIES ARE NOW HOME TO HALF OF THE WORLD’S 6.6 BILLION HUMANS. BY 2030, nearly 5 billion people will live in cities. This special issue explores the enormous implications of the mass embrace of city life. News articles offer a look at how cities are tackling specific problems, a set of Reviews and Perspectives examines trends and demographics arising from(More)