Lesley Lawrenson

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The importance of the chromosome versus the gene as a causative agent in cancer formation has sparked a heated debate. This issue is directly related to two different schools of thought, namely the gene-centric or genome-centric paradigms of cancer research [1–3]. For decades we have essentially ignored the evolutionary nature of complex cancer systems due(More)
BACKGROUND AND PURPOSE Serotonin is a major regulator of structural brain plasticity, which may occur following cortical resection in humans. In this study we used positron emission tomography (PET) with alpha[11C]methyl-l-tryptophan (AMT) to evaluate serotonergic alterations in subcortical structures following cortical resection in children with(More)
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