Leopold Stiebellehner

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The American Thoracic Society-European Respiratory Society classification of idiopathic interstitial pneumonias (IIPs), published in 2002, defines the morphologic patterns on which clinical-radiologic-pathologic diagnosis of IIPs is based. IIPs include seven entities: idiopathic pulmonary fibrosis, which is characterized by the morphologic pattern of usual(More)
PURPOSE To perform a systematic review of the published data concerning maxillomandibular advancement for the treatment of obstructive sleep apnea syndrome. MATERIALS AND METHODS A systematic literature search was performed in the PubMed database. Original articles in the English language were reviewed to obtain information about patient data, success(More)
Primary pulmonary hypertension is a fatal disease causing progressive right heart failure within 3 years after diagnosis. We describe a new concept for treatment of the disease using vasoactive intestinal peptide, a neuropeptide primarily functioning as a neurotransmitter that acts as a potent systemic and pulmonary vasodilator. Our rationale is based on(More)
PURPOSE beyond the pure morphological visual representation, MR imaging offers the possibility to quantify parameters in the healthy, as well as, in pathologic lung parenchyma. Gas exchange is the primary function of the lung and the transport of oxygen plays a key role in pulmonary physiology and pathophysiology. The purpose of this review is to present a(More)
BACKGROUND Pulmonary hypertension is a frequent complication of severe chronic obstructive pulmonary disease (COPD) and a major cause of morbidity and mortality in this condition. Based on the improved survival of these patients due to long term oxygen therapy and the potent and selective pulmonary vasodilation by inhaled nitric oxide, the safety and(More)
OBJECTIVES To evaluate the effect of long-term oral therapy with sildenafil in patients with pulmonary arterial hypertension receiving long-term IV epoprostenol. DESIGN Open, uncontrolled trial. SETTING University hospital. PATIENTS Two patients with primary pulmonary hypertension and one patient with pulmonary arterial hypertension after surgical(More)
ZIELE: Das Vorliegen einer pulmonalen Hypertension ist häufig bei Patienten mit chronisch obstruktiver Lungenerkrankung (COPD) anzutreffen. Der mittlere pulmonalarterielle Druck (mPAP) ist in Ruhe oft nur gering erhöht, zeigt aber einen pathologischen Anstieg unter Belastung. Das Ziel dieser Studie ist es, die Leistungsfähigkeit und den pulmonalen(More)
OBJECTIVE To assess whether long term treatment with epoprostenol might restore primary non-responsiveness to nitric oxide (NO) in patients with primary pulmonary hypertension. METHODS Seven patients with primary pulmonary hypertension receiving intravenous epoprostenol continuously because of failure of NO to influence pulmonary haemodynamics during(More)
The T(1) values of lung parenchyma of 25 patients with fibrosis and emphysema were measured in the entire lung, and the effect of inspiration and expiration was investigated. T(1) map acquisition was based on a snapshot-fast low-angle shot (FLASH) sequence. Lung function and blood gas tests were measured. The study documents reverse respiratory phase(More)