Leontien Ingeborg Geven

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OBJECTIVE To compare the functioning of the medial olivocochlear efferent system between tinnitus patients and control subjects. STUDY DESIGN Prospective, nonrandomized controlled analysis of suppression of otoacoustic emissions with contralateral acoustic stimulation. SETTING Tertiary referral center. PATIENTS Initial analysis of 97 tinnitus patients(More)
Tinnitus is a bothersome phantom sound percept and its neural correlates are not yet disentangled. Previously published papers, using [(18)F]-fluoro-deoxyglucose positron emission tomography (FDG-PET), have suggested an increased metabolism in the left primary auditory cortex in tinnitus patients. This unilateral hyperactivity has been used as a target in(More)
HYPOTHESIS The role of the corticofugal efferent auditory system in the origin or maintenance of tinnitus is currently mostly overlooked. Changes in the balance between excitation and inhibition after an auditory trauma are likely to play a role in the origin of tinnitus. The efferent auditory system can be expected to be involved in such changes. (More)
The efferent auditory system is thought to play a role in the origin of tinnitus. Part of this system can be tested in humans with contralateral suppression of otoacoustic emissions. Stimulation of the medial olivocochlear efferent system is responsible for this reduction of otoacoustic emissions after contralateral acoustic stimulation. Previous research(More)
Contents 1 Introduction to the thesis 7 2 Plasticity in tinnitus patients: a role for the efferent auditory system? 19 3 Asymmetry in primary auditory cortex activity in tinnitus patients 37 and controls 4 Contralateral suppression of otoacoustic emissions in tinnitus patients 55 5 Wavelet-analysis demonstrates no abnormality in contralateral 71 suppression(More)
OBJECTIVE To assess the role of the relative length of the posterior rib stump in outcome after transaxillary first rib resection for thoracic outlet syndrome. METHODS All patients with a transaxillary first rib resection between January 1990 and February 2004 were selected. Relative rib stump length was calculated by dividing the length of the posterior(More)
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