Leonid Nazarov

Learn More
The fractal globule state is a popular model for describing chromatin packing in eukaryotic nuclei. Here we provide a scaling theory and dissipative particle dynamics computer simulation for the thermal motion of monomers in the fractal globule state. Simulations starting from different entanglement-free initial states show good convergence which provides(More)
A statistical model describing a fine structure of the intra-chromosome maps obtained by a genome-wide chromosome conformation capture method (Hi-C) is proposed. The model combines hierarchical chain folding with a quenched heteropolymer structure of primary chromatin sequences. It is conjectured that the observed Hi-C maps are statistical averages over(More)
Basing on experimental data, it was established that single administration of 0.5 mg bemitil increased human resistance to carbon oxide in concentration 300 mg/m3. The use of bemitil optimized human body state in the conditions of the complex influence of carbon oxide and extreme heating microclimate.
A group of volunteers was exposed to coaction of carbon dioxide (concentration 300 mg/cu m) and heating microclimate (ambient temperature +50 +/- 2 degrees C, relative humidity 20 +/- 5%), simultaneously they received one of the medicines: placebo, bemitil (0.5 g), bromantane (0.25 g) or bemitil (0.5 g) combined with bromantane (0.25 g). Bromantane (0.25 g)(More)
L. Nazarov, M.V. Tamm, S.K. Nechaev, V.A. Avetisov Physics Department, M.V. Lomonosov Moscow State University, 119992 Moscow, Russia Department of Applied Mathematics, Higher School of Economics, 101000 Moscow, Russia Université Paris-Sud/CNRS, LPTMS, UMR8626, 91405 Orsay, France P.N. Lebedev Physical Institute, RAS, 119991 Moscow, Russia N.N. Semenov(More)
Alexander P. Moscalets, Leonid I. Nazarov, and Mikhail V. Tamm Department of Applied Mathematics, National Research University Higher School of Economics, 101000, Moscow, Russia 2 A.N. Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences, 119991, Moscow, Russia 3 Chemistry Department, Moscow State University, 119991, Moscow,(More)
Experiments were performed to study the effect of carbon monoxide and ammonia on man wearing a protective suit. It was found that hypobaric oxygenation produced a modifying effect on the level of intoxication with these compounds. It is recommended to take into consideration specific environmental effects when standardizing concentrations of toxic(More)
The fractal globule state is a popular model for describing chromatin packing in eukaryotic nuclei. Here we provide a scaling theory and dissipative particle dynamics (DPD) computer simulation for the thermal motion of monomers in the fractal globule state. Simulations starting from different entanglement-free initial states show good convergence which(More)