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Internal Nanoparticle Structure of Temperature-Responsive Self-Assembled PNIPAM-b-PEG-b-PNIPAM Triblock Copolymers in Aqueous Solutions: NMR, SANS, and Light Scattering Studies.
- S. Filippov, A. Bogomolova, M. Cook
- Materials ScienceLangmuir : the ACS journal of surfaces and…
- 18 May 2016
Detailed information is reported on the internal structure of PNIPAM-b-PEG- b-PNIPAM nanoparticles formed from self-assembly in aqueous solutions upon increase in temperature, providing insight into the fundamental processes involved.
Polyelectrolyte pH-Responsive Protein-Containing Nanoparticles: The Physicochemical Supramolecular Approach.
- A. Riabtseva, Leonid I Kaberov, M. Hrubý
- Chemistry, Materials ScienceLangmuir : the ACS journal of surfaces and…
- 12 January 2017
The results showed that trypsin encapsulated into novel pH-sensitive nanocontainers retained more than 50% of its activity after treatment with pepsin compared with nonencapsulated trypsIn, which will contribute both to understanding the principles of and designing next-generation nanoc ontainers.
Novel triphilic block copolymers based on poly(2-methyl-2-oxazoline)–block–poly(2-octyl-2-oxazoline) with different terminal perfluoroalkyl fragments: Synthesis and self-assembly behaviour
Double stimuli-responsive polymer systems: How to use crosstalk between pH- and thermosensitivity for drug depots
Fluorinated 2-Alkyl-2-oxazolines of High Reactivity: Spacer-Length-Induced Acceleration for Cationic Ring-Opening Polymerization As a Basis for Triphilic Block Copolymer Synthesis.
The synthesis of defined triphilic terpolymers with hydrophilic, lyophilic, and fluorophilic blocks is an important challenge as a basis for the development of multicompartment self-assembled…
Polymer Cancerostatics Targeted by Recombinant Antibody Fragments to GD2-Positive Tumor Cells.
A water-soluble polymer cancerostatic actively targeted against cancer cells expressing a disialoganglioside antigen GD2 was designed, synthesized and characterized and proved to be superior to the covalent polymer-scFv conjugate.
Structural characterization of nanoparticles formed by fluorinated poly(2-oxazoline)-based polyphiles
Fluorophilic–Lipophilic–Hydrophilic Poly(2-oxazoline) Block Copolymers as MRI Contrast Agents: From Synthesis to Self-Assembly
This work focuses on the synthesis and self-assembly of triphilic poly(2-oxazoline) triblock copolymers with high fluorine content toward our future aim of developing poly(2-oxazoline) magnetic…
Fluorine-Containing Block and Gradient Copoly(2-oxazoline)s Based on 2-(3,3,3-Trifluoropropyl)-2-oxazoline: A Quest for the Optimal Self-Assembled Structure for 19F Imaging.
The gradient copolymers provide the best 19FMRI signal-to-noise ratio in comparison with the analogue block copolymer structures, making them most promising as 19F MRI contrast agents.