Leonardo Piccini

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The Vie Cave are a suggestive network of roads deeply entrenched in the rock, dating back to the Etruscan civilization; these ancient roads connect various settlements and necropolises existing mainly in the area of Sovana, Sorano and Pitigliano towns (Southern Tuscany, Italy). The Vie Cave are located in a peculiar geomorphological site, characterized by(More)
The GvHD is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Extracorporeal photopheresis (ECP) represents an alternative therapeutic strategy to immunosuppressive therapy. Although ECP is used since 1990s, the mechanism of action has not yet been completely clarified. We analyzed cells collected from(More)
BACKGROUND Leukapheresis for autologous stem cell transplantation represents an efficient technique for the reconstitution of haematopoietic system in patients subjected to a high-dose chemotherapy for the treatment of haematological malignancies. The current regulations emphasise first steps of leukapheresis procedure but do not recommend methods for(More)
The occurrence of the R peak (tR), and the area of the QRS complex (AQRS) are among the features estimated from each ECG wave. To estimate these parameters ECG is traditionally sampled at a high sampling rate (250-500Hz). However, since tR and AQRS are identified by the selective analysis of the QRS complex and since the QRS maximal frequency component is(More)
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