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  • Leonardo F. Ferreira, Paul McDonough, Brad J. Behnke, Timothy I Musch, David C Poole
  • Medicine
  • Respiratory Physiology & Neurobiology
  • 2006 (First Publication: 1 October 2006)
  • We examined how the greater vasodilatory capacity of slow--(ST) versus fast-twitch (FT) muscles impacts the relationship between blood flow (Q ) and O2 uptake (VO2) and, consequently, the O2Continue Reading
  • Gaspar Rogério Chiappa, Audrey Borghi-Silva, +9 authors José Alberto Neder
  • Medicine
  • Journal of applied physiology
  • 2008 (First Publication: 1 May 2008)
  • Patients with chronic obstructive pulmonary disease (COPD) have slowed pulmonary O(2) uptake (Vo(2)(p)) kinetics during exercise, which may stem from inadequate muscle O(2) delivery. However, it isContinue Reading
  • Laura A. A. Gilliam, Leonardo F. Ferreira, +4 authors Michael B. Reid
  • Chemistry, Medicine
  • Journal of applied physiology
  • 2009 (First Publication: 1 December 2009)
  • Cancer patients receiving doxorubicin chemotherapy experience both muscle weakness and fatigue. One postulated mediator of the muscle dysfunction is an increase in tumor necrosis factor-alpha (TNF),Continue Reading
  • Priscila Barros Barbosa, Daniela M. Bravo, José Alberto Neder, Leonardo F. Ferreira
  • Medicine, Chemistry
  • Respiratory Physiology & Neurobiology
  • 2010 (First Publication: 1 August 2010)
  • Muscle vascular dysfunction, a hallmark of chronic diseases such as heart failure and diabetes, impairs the matching of blood flow (Q(m)) to O(2) utilization (V(O(2m))) following exercise onset. OneContinue Reading
  • Sarah M. Senf, Travis M Howard, Bumsoo Ahn, Leonardo F. Ferreira, Andrew R Judge
  • Chemistry, Medicine
  • PloS one
  • 2013 (First Publication: 23 April 2013)
  • Skeletal muscle regeneration following injury is a highly coordinated process that involves transient muscle inflammation, removal of necrotic cellular debris and subsequent replacement of damagedContinue Reading
  • Leonardo F. Ferreira, Jennifer S. Moylan, Laura A. A. Gilliam, Jeffrey D. Smith, Mariana N. Nikolova-Karakashian, Michael B. Reid
  • Biology, Medicine
  • American journal of physiology. Cell physiology
  • 2010 (First Publication: 1 September 2010)
  • Sphingomyelinase (SMase) hydrolyzes membrane sphingomyelin into ceramide, which increases oxidants in nonmuscle cells. Serum SMase activity is elevated in sepsis and heart failure, conditions whereContinue Reading
  • Brandon M Roberts, Gregory S. Frye, Bumsoo Ahn, Leonardo F. Ferreira, Andrew R Judge
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2013 (First Publication: 1 June 2013)
  • Cancer cachexia is a complex metabolic syndrome that is characterized by the loss of skeletal muscle mass and weakness, which compromises physical function, reduces quality of life, and ultimatelyContinue Reading