Leonarda Di Candia

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Inflammatory myofibroblastic tumors (IMT) in the head and neck region are rare neoplasms that generally mimic benign/low-grade neoplasms. Overexpression of anaplastic lymphoma kinase (ALK) has been reported in 50% of IMT cases, secondary to ALK activation by structural rearrangements in the ALK gene, which results in a fusion protein with echinoderm(More)
A mong the pattern recognition receptors (PRRs), the receptor for advanced glycation end-products (RAGE) has been shown to bind many damage-associated molecular patterns (DAMPs, also known as alarmins). DAMPs are released following tissue damage due to both infectious and non-infectious trauma whereby necrotic cells lose membrane integrity, causing their(More)
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