Leonard J. West

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Controlled drinking has recently become a controversial alternative to abstinence as an appropriate treatment goal for alcoholics. In this study we reexamine the evidence underlying a widely cited report by Sobell and Sobell of successful controlled drinking by a substantial proportion of gamma (physically dependent) alcoholic subjects in a behavior therapy(More)
the free enzyme. Similarly, the apparent molecular weight of the slower-migrating band will be lower than that of the free aggregate. In our experiments, the molecular weight of the aggregate appears to be more than twice that of the free enzyme. On this basis, one could propose a dimer-hexamer association. Associations of this type are less favourable(More)